The Nephrology and Hypertension department, University Medical Center Utrecht (UMCU)is world-class in regenerative nephrology, including ASc tubuloid technology, and clinical trials of innovative dialysis technologies. UMCU has in-house ISO 13485 certified medical device prototyping, a validated uremic goat model and IP on breakthrough thrombolytic drugs. Research is truly translational, ranging from fundamental research to animal experiments and clinical trials

https://www.umcutrecht.nl/en/Research/Research-programs/Circulatory-Health

Regenerative Medicine & Stem Cells – UMC Utrecht

The Utrecht Institute for Pharmaceutical Sciences, division of Pharmacology, Utrecht University (UU), has a longstanding expertise in studying kidney tubular transport in experimental systems.

Humanized in vitro systems are being applied that functionally mimic (patients’) kidneys, which includes the use of innovative technologies for 3D advanced tissue cultures such as microfluidics (organs-on-chip technology) biofabrication for tissue engineering, and their functional assessments. The research group plays a prominent role within EUTox

https://www.uu.nl/en/research/utrecht-institute-for-pharmaceutical-sciences-uips

https://www.uu.nl/en/research/pharmacology

Imec Eindhoven (IMEC-NL) has great experience in system architecture & integration of wearable and implantable technology into health care, including on-chip integrated bioimpedance spectroscopy.
IMEC NL plays an active role in the creation of the KHI roadmap for KRT technologies and international MedTech standardization.

https://imec-int.com

Imec Leuven (IMEC-BE) is a world-leading not-for-profit research and innovation hub in nanoelectronics and digital technologies. Imec offers a unique combination of widely acclaimed leadership in microchip technology and profound software/ICT expertise, as well as a world-class infrastructure (200 mm and 300 mm wafer processing) with partners across a multitude of industries. Imec creates ground-breaking innovation in application domains such as healthcare, smart cities & mobility, logistics & manufacturing, energy & education with proven societal impact.

https://www.imec-int.com/en

The Laboratory for Interdisciplinary Physics (LIPhy, CNRS) is an academic research lab focused on soft matter physics and its interfaces with biology and chemistry. The group led by Lionel Bureau works on thin polymer coatings for the control of interactions between surfaces and biological objects. Of particular interest is the development of bio-inspired coatings mimicking the in-vivo role of the endothelial glycocalyx, a biopolymer coating lining the lumen of blood vessels and controlling the interactions between flowing blood cells and the vascular walls

https://liphy.univ-grenoble-alpes.fr/en/modi

Optofluid Technologies OÜ (OFT) is an Estonian SME that converts optical sensing technologies from Tallinn University of Technology into commercial sensing modules. The company is targeting drastic miniaturization (for which cooperation with IMEC will be an enabler). OFT has a proven track record and a broad team with strong competencies in biofluid optics, kidney replacement therapy monitoring, uremic toxins and sensor technology.

https://taltech.ee/en/centre-biomedical-engineering

ME-SEP Is an innovative research and engineering SME providing technical and business solutions in the field of membrane technology. ME-SEP offers support in technology transfer of flat-sheet and hollow-fiber membrane production, membrane module manufacturing plus construction and validation of separation systems for gas & liquid mixtures. Realizing the test setups for the targeted nano-filters will make ME-SEP creating the “de-facto standard” for testing such membranes (because the existing test standards will likely need to be overhauled to achieve this).

https://www.me-sep.com/